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Double mutants of IGF-2 and IGF-1 receptor and of IGF-1/IGF-2 are phenotypically identical, showing a dwarfism with 30 % of the normal size

D., Fahey, J

IGF-1 Elevation Increased growth hormone stimulates the liver to produce more IGF-1 (insulin-like growth factor 1), which mediates many of GH's downstream benefits including muscle growth, tissue repair, and fat metabolism

This may also reflect deeper GH-related recovery and parasympathetic activation

For deeper analysis of these differences, see the article on ipamorelin vs

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